منابع مشابه
Chlorpropamide in Parkinson's Disease
disease includes the following observations, but their significance is not yet clear: (1) There is evidence of a connection between abnormal glucose tolerance and post' encephalitic Parkinson's disease (Gillhespy and Paton, i960; Terrana and Adragn^ 1951). McCowan, Harris and Mann (1926) give glucose tolerance curves for a group of patients with post-encephalitic Parkinsonism which are clearly ...
متن کاملThe chlorpropamide alcohol flush.
Many non-insulin dependent diabetics (NIDDs) on the sulphonylurea chlorpropamide experience intense facial flushing after taking alcohol even in small amounts. This chlorpropamide alcohol flush (CPAF) was first recognized within months of the introduction of the drug in the 1950s [ l ] but, although an alcohol flush occasionally occurs with tolbutamide [ 2 , 31, it has not been reported with ot...
متن کاملHypoglycaemic coma with chlorpropamide.
MILD hypoglycaemic reactions are well recognized as a complication of chlorpropamide therapy, and have been estimated as occurring in 7% of all cases (Stowers & Bewsher, 1962). Severe hypoglycaemic coma due to this drug seems, however, to have been infrequently recognized, and we have been able to find only four isolated reports of this condition in the literature (Coates & Robbins, 1959; Bloch...
متن کاملChlorpropamide-induced haemolytic anaemia.
A newly diagnosed diabetic patient, recently started on chlorpropamide, required emergency admission because of sudden onset of weakness and syncope. In vitro testing confirmed the diagnosis of chlorpropamide induced haemolysis, and withdrawal of the drug resulted in clinical recovery.
متن کاملResponse of antidiuretic hormone to chlorpropamide.
Response of antidiuretic hormone to chlorpropamide Chlorpropamide has been used to treat diabetes insipidus since 1966,1 but its mode of action is still not entirely clear. There is good agreement that it augments the renal effects of endogenous antidiuretic hormone,2 but it might also cause pituitary release.3 To help clarify this we have measured serial plasma concentrations of antidiuretic h...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1979
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1979.tb00904.x